Infliximab - CISMeF

Preferred Label : Infliximab;

NCIt synonyms : Avakine;

NCIt definition : A recombinant chimeric, mouse-human monoclonal antibody directed against tumor necrosis factor alpha (TNF-alpha), a protein involved in inflammation, cell survival, and apoptosis. Infliximab may be pro- apoptotic or anti-apoptotic, depending on cell type. (NCI04);

Alternative definition : NCI-GLOSS: A monoclonal antibody that blocks the action of a cytokine called tumor necrosis factor alfa. It is being studied in the treatment and prevention of weight loss and loss of appetite in patients with advanced cancer. It belongs to the family of drugs called monoclonal antibodies.;

UNII : B72HH48FLU;

CAS number : 170277-31-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 170277-31-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Remicade; Remsima;

Molecule name : cA2;

NSC code : 728729;

Codes from synonyms : CDR0000269421;

Details

Origin ID

C1789;

UMLS CUI

C0666743;

Automatic exact mappings (from CISMeF team)
- infliximab [medical devices type]
CISMeF manual mappings
- Infliximab [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Infliximab [MeSH Descriptor]
- Infliximab [Substance BNPC]
- Infliximab (substance) [SNOMED CT concept]
- Product containing infliximab (medicinal product) [SNOMED CT concept]
- inFLIXimab [LOINC component]
- infliximab [ATC Code]
- infliximab [MeSH concept]
Validated automatic mappings to BTNT
- infliximab [ATC Code]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_target
- Tumor Necrosis Factor [NCIt concept]
is_component_of_chemotherapy_regimen
- Docetaxel/Infliximab [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients