Serum Amyloid A-1 Protein

Preferred Label : Serum Amyloid A-1 Protein;

NCIt synonyms : Serum Amyloid A1; Amyloid Fibril Protein AA; SAA; Tumor Protein P53 Inducible Protein 4; SAA1; Serum Amyloid A Protein; Amyloid Protein A Precursor;

NCIt definition : Serum amyloid A-1 protein (122 aa, 14 kDa) is encoded by the human SAA1 gene. This protein plays a role in heparin binding and acute phase inflammatory responses.;

NCIt note : Serum amyloid A-1 protein is processed to remove 18 N-terminal amino acids prior to secretion. This product can be cleaved further to generate six other forms: amyloid protein AA (comprised of amino acids 19-94), serum amyloid protein A(2-104) (comprised of amino acids 20-122), serum amyloid protein A(2-103) (comprised of amino acids 20-121), serum amyloid protein A(2-102) (comprised of amino acids 20-120), serum amyloid protein A(3-104) (comprised of amino acids 21-122) and serum amyloid protein A(4-101) (comprised of amino acids 22-119). (UniProt);

Details

Origin ID

C178652;

UMLS CUI

C5551373;

Automatic exact mappings (from CISMeF team)
- Amyloid A [LOINC component]
- Serum amyloid A protein [MedDRA Preferred Term]
- Serum amyloid a1 [OMIM gene]
- Serum amyloid protein (substance) [SNOMED CT concept]
- serum amyloid A protein [MeSH concept]
OMIM relation
- Serum amyloid a1 [OMIM gene]
See also inter- (CISMeF)
- amyloid beta-protein precursor [MeSH Descriptor]
- serum amyloid A1 [HGNC gene]
- serum amyloid A1 [ORDO Gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- Serum amyloid A protein (substance) [SNOMED CT concept]
- serum amyloid A protein [MeSH Descriptor]
- serum amyloid a protein [SNOMED Notion]
gene_encodes_gene_product
- Immunoprotein Gene [NCIt concept]
- SAA1 Gene [NCIt concept]
gene_product_expressed_in_tissue
- Plasma [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Serum Amyloid A [NCIt concept]
gene_product_has_chemical_classification
- Circulating Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- Heparin Binding [NCIt concept]
- Immune System Process [NCIt concept]
- Immunity [NCIt concept]

Keyword's position in hierarchy(ies) :

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