MeSH definition : A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN
SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide,
AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE
PLAQUES.;
MeSH synonym : beta amyloid protein precursor; beta-protein precursor, amyloid; beta-amyloid protein precursor; amyloid protein precursor; amyloid a4 protein precursor; amyloid beta precursor protein; protease nexin II; nexin II, protease; protease nexin 2; nexin 2, protease; amyloid beta protein precursor;
A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN
SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide,
AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE
PLAQUES.