Pyruvate Dehydrogenase Kinase

Preferred Label : Pyruvate Dehydrogenase Kinase;

NCIt synonyms : PDK Family; Pyruvate Dehydrogenase Kinase, Mitochondrial; [Pyruvate Dehydrogenase (Acetyl-Transferring)] Kinase, Mitochondrial; PDH Kinase; Pyruvate Dehydrogenase Kinase Isozyme, Mitochondrial; PDK; PDHK; Pyruvate Dehydrogenase Kinase Family; [Pyruvate Dehydrogenase] Kinase Isozyme, Mitochondrial; [Pyruvate Dehydrogenase (Acetyl-Transferring)] Kinase;

NCIt definition : A family of kinases that regulate glucose and fatty acid metabolism by phosphorylating and inactivating the mitochondrial enzyme pyruvate dehydrogenase.;

NCI Metathesaurus CUI : CL1375562;

Details

Origin ID

C178566;

UMLS CUI

C5197822;

Currated CISMeF NLP mapping
- Pyruvate Dehydrogenase Acetyl-Transferring Kinase [MeSH Descriptor]
- Pyruvate Dehydrogenase Acetyl-Transferring Kinase [MeSH concept]
See also inter- (CISMeF)
- Pyruvate dehydrogenase (lipoamide) kinase (substance) [SNOMED CT concept]
- [pyruvate dehydrogenase (lipoamide)] kinase [SNOMED Notion]
- pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Pyruvate Dehydrogenase Acetyl-Transferring Kinase [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Kinase Family Gene [NCIt concept]
gene_product_has_biochemical_function
- Phosphotransferase [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
is_target
- Sodium Dichloroacetate [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients