Pyruvate Dehydrogenase Acetyl-Transferring Kinase

Preferred Label : Pyruvate Dehydrogenase Acetyl-Transferring Kinase;

MeSH definition : A pyruvate dehydrogenase kinase isozyme located in the mitochondria which converts PYRUVATE to ACETYL CoA in the CITRIC ACID CYCLE, phosphorylates SERINE residues on pyruvate dehydrogenase using ATP, and plays a key role in the regulation of GLUCOSE and fatty acid metabolism.;

MeSH synonym : Pyruvate Dehydrogenase Acetyl Transferring Kinase; PDH Kinase; Kinase, PDH; Pyruvate Dehydrogenase (Lipoamide) Kinase; Pyruvate Dehydrogenase (Acetyl-Transferring) Kinase; Pyruvate Dehydrogenase Kinase; Dehydrogenase Kinase, Pyruvate; Kinase, Pyruvate Dehydrogenase;

MeSH Related Number : EC 2.7.11.2; SI5WM8U605; XEX0252SGP;

Wikipedia link : https://en.wikipedia.org/wiki/Pyruvate dehydrogenase kinase;

Details

Origin ID

D000081382;

UMLS CUI

C5197822;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Pyruvate Dehydrogenase Kinase [NCIt concept]
- Pyruvate dehydrogenase (lipoamide) kinase (substance) [SNOMED CT concept]
- [pyruvate dehydrogenase (lipoamide)] kinase [SNOMED Notion]
Record concept(s)
- Pyruvate Dehydrogenase Acetyl-Transferring Kinase [MeSH concept]
Related MeSH Supplementary Concept(s)
- PDK1 protein, human [MeSH Supplementary Concept]
- PDK2 protein, human [MeSH Supplementary Concept]
- PDK3 protein, human [MeSH Supplementary Concept]
- PDK4 protein, human [MeSH Supplementary Concept]
- Pdk1 protein, mouse [MeSH Supplementary Concept]
- Pdk1 protein, rat [MeSH Supplementary Concept]
- Pdk2 protein, mouse [MeSH Supplementary Concept]
- Pdk2 protein, rat [MeSH Supplementary Concept]
- Pdk3 protein, mouse [MeSH Supplementary Concept]
- Pdk3 protein, rat [MeSH Supplementary Concept]
- Pdk4 protein, mouse [MeSH Supplementary Concept]
- Pdk4 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Pyruvate Dehydrogenase Kinase [NCIt concept]

Keyword's position in hierarchy(ies) :

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