PHD Finger Protein 1

Preferred Label : PHD Finger Protein 1;

NCIt synonyms : Testicular Tissue Protein Li 140; hPCl1; Protein PHF1; PHF1; hPHF1; Polycomb-Like Protein 1;

NCIt definition : PHD finger protein 1 (567 aa, 62 kDa) is encoded by the human PHF1 gene. This protein is involved in DNA damage responses, binding to trimethylated lysine 36 in histone H3 (H3K36me3) and recruitment of the PRC2 complex.;

Details

Origin ID

C178361;

UMLS CUI

C1308534;

Automatic exact mappings (from CISMeF team)
- PHD finger protein 1 [HGNC gene]
- Phd finger protein 1 [OMIM gene]
OMIM relation
- Phd finger protein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PHF1 protein, human [MeSH Supplementary Concept]
- PHF1 protein, human [MeSH concept]
gene_encodes_gene_product
- PHF1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- PHD Finger [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Structural Process [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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