" /> SORT1 wt Allele - CISMeF





Preferred Label : SORT1 wt Allele;

NCIt synonyms : NT3; Low Density Lipoprotein Cholesterol Level Quantitative Trait Locus 6 Gene; LDLCQ6; Sortilin 1 wt Allele; Low Density Lipoprotein Cholesterol Level QTL6 Gene; LDL-C QTL6; Gp95; Neurotensin Receptor, 100-kD Gene; NTR3;

NCIt definition : Human SORT1 wild-type allele is located in the vicinity of 1p13.3 and is approximately 88 kb in length. This allele, which encodes sortilin protein, plays a role in protein trafficking and neuroactive peptide-dependent signaling. The minor allele for a noncoding polymorphism in the promoter for this gene creates a CCAAT/enhancer binding protein transcription factor binding site and may result in increased hepatic expression of the encoded protein, decreased circulating cholesterol and decreased risk for myocardial infarction.;

NCI Metathesaurus CUI : CL1647975;

GenBank Accession Number : BC023542;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
19/05/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.