Transducin Beta-Like Protein 1 Family

Preferred Label : Transducin Beta-Like Protein 1 Family;

NCIt synonyms : Transducin Beta-Like 1; TBL1; TBL1 Family Protein; Transducin Beta-Like Protein 1; Tbl-1;

NCIt definition : A family of comprised of two proteins that are encoded by similar genes on the X and Y chromosomes and are found in nuclear receptor corepressor protein complexes (NCoR/SMRT), which regulate nuclear receptor-dependent transcriptional repression. Transducin beta-like protein 1 (TBL1) family members may recruit the 19S proteasome complex to NCoR/SMRT complexes and promote complex degradation.;

NCI Metathesaurus CUI : CL1647679;

Details

Origin ID

C178138;

UMLS CUI

C5553016;

Automatic exact mappings (from CISMeF team)
- Transducin-beta-like 1, X-linked [OMIM gene]
Biochemical function of gene products
- F-Box-Like/WD Repeat-Containing Protein TBL1X [NCIt concept]
- F-Box-Like/WD Repeat-Containing Protein TBL1Y [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_plays_role_in_biological_process
- Translational Regulation [NCIt concept]
is_target
- Tegavivint [NCIt concept]

Keyword's position in hierarchy(ies) :

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