" /> Atrasentan Hydrochloride - CISMeF





Preferred Label : Atrasentan Hydrochloride;

NCIt synonyms : (2R,3R,4S)-4-(1,3-Benzodioxo-5-yl)-1-(2-(dibutylamino)-2-oxoethyl)-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic Acid Monohydrochloride; Atrasentan;

NCIt definition : The orally available hydrochloride salt of pyrrolidine-3-carboxylic acid with potential antineoplastic activity. As a selective antagonist of the endothelin-A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.;

UNII : E4G31X93ZA;

InChIKey : IJFUJIFSUKPWCZ-SQMFDTLJSA-N;

CAS number : 195733-43-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 195733-43-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Xinlay;

Molecule name : ABT-627; ( )-A 127722;

Chemical formula : C29H38N2O6.ClH;

NSC code : 720763;

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12/05/2024


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