Atrasentan - CISMeF

Preferred Label : Atrasentan;

MeSH definition : A pyrrolidine and benzodioxole derivative that acts a RECEPTOR, ENDOTHELIN A antagonist. It has therapeutic potential as an antineoplastic agent and for the treatment of DIABETIC NEPHROPATHIES.;

MeSH hyponym : A-127722; A127722; A-127722.5; A 127722.5; A127722.5; A-147627; A147627; ABT-627; ABT627;

MeSH CAS label : 3-Pyrrolidinecarboxylic acid, 4-(1,3-benzodioxol-5-yl)-1-(2-(dibutylamino)-2-oxoethyl)-2-(4-methoxyphenyl)-, (2R,3R,4S)-;

MeSH Related Number : E4G31X93ZA;

UNII : V6D7VK2215;

Details

Origin ID

D000077868;

UMLS CUI

C0935914;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Atrasentan [NCIt concept]
MeSH indexing information
- carbon radioisotopes [MeSH Descriptor]
- receptors, endothelin [MeSH Descriptor]
- stereoisomerism [MeSH Descriptor]
Pharmacological action(s)
- Endothelin A Receptor Antagonists [MeSH Descriptor]
- antineoplastic agents [MeSH Descriptor]
Record concept(s)
- (11C)ABT-627 [MeSH concept]
- 2-(4-Methoxyphenyl)-4-(1,3-benzodioxol-5-yl)-1-(((dibutylamino)carbonyl)methyl)pyrrolidine-3-carboxylic acid [MeSH concept]
- A 127722 [MeSH concept]
- A 147627 [MeSH concept]
- ABT 627 [MeSH concept]
- Atrasentan Hydrochloride [MeSH concept]
- atrasentan [MeSH concept]
- xinlay [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Atrasentan [NCIt concept]
Validated automatic mappings to BTNT
- Atrasentan Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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