NCIt definition : Nuclear autoantigen Sp-100 (879 aa, 100 kDa) is encoded by the human SP100 gene.
This protein is involved in PML body function, transcriptional regulation and DNA
binding.;
Alternative definition : CDISC: An antigen encoded by the SP100 gene and is involved in promyelocytic leukemia
nuclear (PML) body function, transcriptional regulation and DNA binding. It can be
considered as an autoantigen and is commonly associated with the autoimmune disease
primary biliary cholangitis.;