Transmembrane 4 L6 Family Member 1

Preferred Label : Transmembrane 4 L6 Family Member 1;

NCIt synonyms : TM4SF1; L6; Tumor-Associated Antigen L6; L6 Antigen; L6 Cell Surface Antigen; TM4SF1t; Membrane Component Chromosome 3 Surface Marker 1; Tumor-Associated Antigen-L6; Membrane Component, Chromosome 3, Surface Marker 1; Transmembrane 4 Superfamily Member 1;

NCIt definition : Transmembrane 4 L6 family member 1 (202 aa, 22 kDa) is encoded by the human TM4SF1 gene. This protein may be involved in cellular morphology and integrin signaling.;

NCIt note : Transmembrane 4 L6 family member 1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. (RefSeq);

Details

Origin ID

C17581;

UMLS CUI

C0167206;

OMIM relation
- Transmembrane 4 L six family member 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- TM4SF1 protein, human [MeSH Supplementary Concept]
- TM4SF1 protein, human [MeSH concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- TM4SF1 Gene [NCIt concept]
gene_product_affected_by_chemical_or_drug
- Monoclonal Antibody L6 [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_is_biomarker_type
- Tumor Marker [NCIt concept]
is_target
- Autologous Anti-TM4SF1 CAR-T Cells [NCIt concept]

Keyword's position in hierarchy(ies) :

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