" /> NLR Family CARD Domain-Containing Protein 4 - CISMeF





Preferred Label : NLR Family CARD Domain-Containing Protein 4;

NCIt synonyms : Ipaf; Caspase Recruitment Domain-Containing Protein 12; ICE-Protease Activating Factor; Clan Protein; Ice Protease-Activating Factor; NLRC4; CARD, LRR, And NACHT-Containing Protein;

NCIt definition : NLR family CARD domain-containing protein 4 (1024 aa, 116 kDa) is encoded by the human NLRC4 gene. This protein is involved in the positive regulation of caspase activation, cytokine expression and pyroptosis of macrophages.;

NCIt note : There are at least 4 isoforms of the NLR family CARD domain-containing protein 4 produced by alternative splicing of the NLRC1 gene. (UniProt);

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31/07/2025


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