Plastin-2 - CISMeF

Preferred Label : Plastin-2;

NCIt synonyms : Lymphocyte Cytosolic Protein 1; Plastin 2; Lymphocyte Cytosol Polypeptide 64-KD; LC64P; LCP1; L-Plastin; Lymphocyte Cytosolic Protein-1; Epididymis Secretory Protein Li 37; LCP-1;

NCIt definition : Plastin-2 (627 aa, 70 kDa) is encoded by the human LCP1 gene. This protein is involved in both actin binding and T-cell activation.;

NCIt note : Plastin-2 contains two EF-hand calcium-binding domains, a calmodulin-binding site, and two tandem actin-binding domains. (OMIM);

Details

Origin ID

C17511;

UMLS CUI

C1429361;

Currated CISMeF NLP mapping
- L-plastin [MeSH concept]
OMIM relation
- Lymphocyte cytosolic protein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- LCP1 protein, human [MeSH concept]
- LCP1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytoskeletal Gene [NCIt concept]
- LCP1 Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- T-Lymphocyte [NCIt concept]
gene_product_has_associated_anatomy
- Cytoskeleton [NCIt concept]
gene_product_has_biochemical_function
- Actin-Binding Protein [NCIt concept]
- Calcium Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- EF-Hand Domain [NCIt concept]
gene_product_is_biomarker_type
- Tumor Marker [NCIt concept]
gene_product_malfunction_associated_with_disease
- B-Cell Non-Hodgkin Lymphoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Binding [NCIt concept]
- Cell Movement Process [NCIt concept]
- Cytoskeletal Modeling [NCIt concept]
- Cytoskeletal Process [NCIt concept]
- Regulation of Cell Shape [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients