T-Cell Leukemia Homeobox Protein 1

Preferred Label : T-Cell Leukemia Homeobox Protein 1;

NCIt synonyms : Proto-Oncogene Tcl-3; HOX11 Protein; TCL3 Protein; T-Cell Leukemia 3 Protein; T-Cell Leukemia/Lymphoma Protein 3; Homeobox Protein Hox-11; TLX1; Homeo Box 11; HOX11; Homeobox Protein HOX11;

NCIt definition : T-cell leukemia homeobox protein 1 (330 aa, 34 kDa) is encoded by the human TLX1 gene. This protein plays a role in the modulation of transcription.;

NCIt note : T-cell leukemia homeobox protein 1 binds to the DNA sequence 5'-GGCGGTAAGTGG-3'. (UniProt);

Details

Origin ID

C17497;

UMLS CUI

C0122269;

OMIM relation
- T-cell leukemia, homeobox 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Oncogene protein TCL3 (substance) [SNOMED CT concept]
- oncogene protein tcl3 [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- TLX1 Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Homeobox Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Homeo Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Survival [NCIt concept]
- DNA Binding [NCIt concept]
- Organogenesis [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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