Myb-Related Protein B

Preferred Label : Myb-Related Protein B;

NCIt synonyms : B-MYB Protein; Myb-Like Protein 2; MYBL2; BMYB Gene Product; B-Myb; BMYB;

NCIt definition : Myb-related protein B (700 aa, 79 kDa) is encoded by the human MYBL2 gene. This protein is involved in the regulation of gene expression, cell proliferation and cell differentiation.;

NCIt note : B-MYB Protein is essential during cell cycle progression; MYBL2 activates CDC2 and cyclin D1 gene expression in proliferating fibroblasts. MYBL2 expression is regulated at the G1/S transition, and its transcription relies on E2F activity in a cell cycle-dependent manner. (OMIM);

Details

Origin ID

C17401;

UMLS CUI

C1505106;

OMIM relation
- Myb protooncogene like 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MYBL2 protein, human [MeSH Supplementary Concept]
- MYBL2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- MYBL2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_is_element_in_pathway
- E2F Transcription Factor Pathway [NCIt concept]
gene_product_is_physical_part_of
- DREAM Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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