Preferred Label : JAK Inhibitor;

NCIt synonyms : Janus Kinase Inhibitor;

NCIt related terms : JAK inhibitors;

NCIt definition : Any agent that targets, binds to and inhibits the activity of one or more of the Janus kinase family of enzymes.;

Alternative definition : ACC/AHA: A substance that inhibits the biological action of tyrosine-protein kinase JAK1, an enzyme that plays a key role in certain types of cancer and cytokine signaling;

NCI Metathesaurus CUI : CL1406090;

Details


Main resources

You can consult :


Janus Kinase Inhibitors and the Risk of Major Adverse Cardiovascular Events, Thrombosis (Including Fatal Events) and Malignancy
https://recalls-rappels.canada.ca/fr/avis-rappel/inhibiteurs-janus-kinase-et-risque-manifestation-cardiovasculaire-grave-thrombose-y
2022
false
false
false
Canada
French
English
Janus Kinase Inhibitors
pharmacovigilance note
cardiovascular diseases
thrombosis
neoplasms
abrocitinib
Fedratinib
ruxolitinib
administration, oral
baricitinib
JAK Inhibitor
upadacitinib
tofacitinib
canada

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