Fluorine F 18 PSMA-1007

Preferred Label : Fluorine F 18 PSMA-1007;

NCIt synonyms : Fluorine-18 PSMA-1007; 18F-PSMA-1007; [18F]-PSMA-1007; PSMA-1007 F-18; 18FPSMA-1007; F-18-PSMA-1007;

NCIt definition : A radioconjugate containing the human prostate-specific membrane antigen (PSMA)-targeting ligand, PSMA-1007, labeled with the radioisotope fluorine F 18, with potential imaging activity using positron emission tomography/computed tomography (PET/CT). Upon administration of fluorine F 18 PSMA-1007, the PSMA-1007 moiety targets and binds to PSMA-expressing tumor cells. This allows for visualization of PSMA-expressing cells upon imaging. PSMA, a tumor-associated antigen (TAA) and type II transmembrane protein, is expressed on the membrane of prostatic epithelial cells and strongly overexpressed in prostate cancer (PCa) cells, with its level rising with increasing tumor differentiation and in hormone-refractory cancers.;

UNII : F1CB00L2RH;

CAS number : 2093321-19-6;

NCI Metathesaurus CUI : CL972323;

Details

Origin ID

C167348;

UMLS CUI

C5238480;

Semantic type(s)
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- PSMA-1007 (18F) [ATC Code]
Validated automatic mappings to BTNT
- PSMA-1007 (18F) [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Glutamate Carboxypeptidase 2 [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients