DNA Polymerase Alpha

Preferred Label : DNA Polymerase Alpha;

NCIt synonyms : Alpha DNA polymerase;

NCIt definition : An enzyme that plays major roles in DNA metabolism. The protein, which exhibits bidirectional nuclease activity is required for both DNA synthesis and repair. DNA polymerase alpha is most active in dividing cells, and is primarily involved with lagging strand synthesis.;

Details

Origin ID

C16510;

UMLS CUI

C0012888;

Automatic exact mappings (from CISMeF team)
- DNA-directed DNA polymerase activity [GO term]
Currated CISMeF NLP mapping
- DNA polymerase I [MeSH concept]
- dna polymerase i [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- DNA polymerase I [MeSH concept]
- dna polymerase i [MeSH Descriptor]
gene_product_affected_by_chemical_or_drug
- Fludarabine Phosphate [NCIt concept]
gene_product_has_biochemical_function
- DNA-directed DNA Polymerase [NCIt concept]
gene_product_has_organism_source
- Bacteria [NCIt concept]
is_target
- Fludarabine Phosphate [NCIt concept]

Keyword's position in hierarchy(ies) :

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