dna polymerase i

Preferred Label : dna polymerase i;

MeSH definition : A DNA-dependent DNA polymerase characterized in prokaryotes and may be present in higher organisms. It has both 3'-5' and 5'-3' exonuclease activity, but cannot use native double-stranded DNA as template-primer. It is not inhibited by sulfhydryl reagents and is active in both DNA synthesis and repair. EC 2.7.7.7.; A DNA-dependent DNA polymerase characterized in prokaryotes and may be present in higher organisms. It has both 3'-5' and 5'-3' exonuclease activity, but cannot use native double-stranded DNA as template-primer. It is not inhibited by sulfhydryl reagents and is active in both DNA synthesis and repair.;

MeSH synonym : klenow fragment; dna-dependent dna polymerase i; dna dependent dna polymerase i; dna polymerase alpha; polymerase alpha, dna; DNA pol I;

CISMeF synonym : pol i; polymerase i, dna;

Registry Number MeSH : EC 2.7.7.-;

Wikipedia link : https://en.wikipedia.org/wiki/Klenow fragment;

Is substance : O;

UNII : EC 2.7.7.7;

Details

Origin ID

D004256;

UMLS CUI

C0012888;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- DNA Polymerase Alpha [NCIt concept]
False automatic mappings
- RNA Polymerase I [NCIt concept]
Indexing information
- DNApol-theta protein, Drosophila [MeSH Supplementary Concept]
- dehydroeburiconic acid [MeSH Supplementary Concept]
- manzamenone A [MeSH Supplementary Concept]
- plakevulin A [MeSH Supplementary Concept]
- poly(malate) [MeSH Supplementary Concept]
- untenone A [MeSH Supplementary Concept]
Record concept(s)
- DNA polymerase I [MeSH concept]
Related MeSH Supplementary Concept(s)
- DNA polymerase I (2-87) [MeSH Supplementary Concept]
- DNA polymerase I (728-777) [MeSH Supplementary Concept]
- DNA polymerase alpha-primase [MeSH Supplementary Concept]
- INCURVATA2 protein, arabidopsis [MeSH Supplementary Concept]
- MIP1 protein, S cerevisiae [MeSH Supplementary Concept]
- POL1 protein, S cerevisiae [MeSH Supplementary Concept]
- POLA2 protein, human [MeSH Supplementary Concept]
- pol1 protein, S pombe [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- DNA Polymerase Alpha [NCIt concept]

Keyword's position in hierarchy(ies) :

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