Grainyhead-Like Protein 2 Homolog

Preferred Label : Grainyhead-Like Protein 2 Homolog;

NCIt synonyms : Transcription Factor CP2-Like 3; Grainyhead-Like 2; GRHL2; Brother of Mammalian Grainyhead; Brother-of-MGR;

NCIt definition : Grainyhead-like protein 2 homolog (625 aa, 71 kDa) is encoded by the human GRHL2 gene. This protein plays a role in neurulation and the morphogenesis and maintenance of epithelially derived tissues.;

NCIt note : Grainyhead-like protein 2 homolog binds to the consensus DNA sequence 5'-AACCGGTT-3'. (UniProt);

Details

Origin ID

C162374;

UMLS CUI

C1173919;

OMIM relation
- Grainyhead-like 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- GRHL2 protein, human [MeSH Supplementary Concept]
- GRHL2 protein, human [MeSH concept]
gene_encodes_gene_product
- GRHL2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transcriptional Activation Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Embryogenesis [NCIt concept]
- Histogenic Process [NCIt concept]
- Morphogenesis [NCIt concept]
- Organogenesis [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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