Protein Lin-9 Homolog

Preferred Label : Protein Lin-9 Homolog;

NCIt synonyms : Type I Interferon Receptor Beta Chain-Associated Protein; HuLin-9; hLin-9; pRB-Associated Protein; Rb Related Pathway Actor; TUDOR Gene Similar Protein; LIN9; Beta Subunit-Associated Regulator of Apoptosis;

NCIt definition : Protein lin-9 homolog (542 aa, 62 kDa) is encoded by the human LIN9 gene. This protein plays a role in the G1/S transition of the cell cycle.;

NCIt note : Protein lin-9 homolog is part of the dimerization partner, RB-like, E2F and multi-vulval class B (DREAM) complex. The DREAM complex modulates the expression of cell cycle-dependent genes.;

NCI Metathesaurus CUI : CL937865;

Details

Origin ID

C158451;

UMLS CUI

C4761512;

Automatic exact mappings (from CISMeF team)
- Lin9 dream muvb core complex component [OMIM gene]
- lin-9 DREAM MuvB core complex component [HGNC gene]
OMIM relation
- Lin9 dream muvb core complex component [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- Cell Cycle Gene [NCIt concept]
- LIN9 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Regulatory Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
gene_product_is_physical_part_of
- DREAM Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- Negative Regulation of G0 to G1 Transition [NCIt concept]
- Negative Regulation of G1 to S Transition [NCIt concept]

Keyword's position in hierarchy(ies) :

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