Age-Related Clonal Hematopoiesis

Preferred Label : Age-Related Clonal Hematopoiesis;

NCIt synonyms : ARCH;

NCIt definition : The gradual, clonal expansion of hematopoietic stem and progenitor cells carrying specific, disruptive, and recurrent genetic variants, in individuals without clear diagnosis of hematological malignancies. It is associated with an increased risk of developing hematologic cancers.;

NCI Metathesaurus CUI : CL556354;

Details

Origin ID

C155821;

UMLS CUI

C4722404;

Automatic exact mappings (from CISMeF team)
- Zinc finger- and btb domain-containing protein 8, opposite strand [OMIM gene]
- arcuate nucleus of hypothalamus [UBERON concept]
Currated CISMeF NLP mapping
- Age-related Clonal Hematopoiesis [MeSH concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Peut être observé dans la(les) pathologie(s)
- Clonal Hematopoiesis of Indeterminate Potential [NCIt concept]
Semantic type(s)
- Finding [UMLS semantic type]
Validated automatic mappings to NTBT
- Clonal Hematopoiesis [MeSH Descriptor]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_has_abnormal_cell
- Abnormal Hematopoietic and Lymphoid Cell [NCIt concept]
disease_has_finding
- Monoclonal Cellular Population Present [NCIt concept]
- Monoclonal Hematopoietic Stem and Progenitor Cells Present [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]

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