MeSH definition : Expansion of blood cells arising from mutant HEMATOPOIETIC STEM CELLS often related
to aging. Mutations on epigenetic regulator genes are common in clonal hematopoiesis
and may be a risk factor for HEMATOLOGIC NEOPLASMS and other cardiovascular diseases.
When variant allele fraction is at least 2% and is present in the absence of severe
cytopenias it is referred to as clonal hematopoiesis of indeterminate potential (CHIP).;
MeSH synonym : Hematopoiesis, Clonal;
MeSH hyponym : Age related Clonal Hematopoiesis; Clonal Hematopoiesis, Age-related; Hematopoiesis, Age-related Clonal; ARCH Age-related Clonal Hematopoiesis; ARCH Age related Clonal Hematopoiesis; Clonal Cytopenia of Undetermined Significance; CCUS Clonal Cytopenia of Undetermined Significance; Clonal Hematopoiesis of Indeterminate Potential; ICUS Idiopathic Cytopenias of Undetermined Significance;
Expansion of blood cells arising from mutant HEMATOPOIETIC STEM CELLS often related
to aging. Mutations on epigenetic regulator genes are common in clonal hematopoiesis
and may be a risk factor for HEMATOLOGIC NEOPLASMS and other cardiovascular diseases.
When variant allele fraction is at least 2% and is present in the absence of severe
cytopenias it is referred to as clonal hematopoiesis of indeterminate potential (CHIP).