Transcriptional Regulator Kaiso

Preferred Label : Transcriptional Regulator Kaiso;

NCIt synonyms : Kaiso Transcription Factor; ZBTB33; Zinc Finger- and BTB Domain-Containing Protein 33; Zinc Finger and BTB Domain-Containing Protein 33;

NCIt definition : Transcriptional regulator Kaiso (672 aa, 74 kDa) is encoded by the human ZBTB33 gene. This protein plays a role in DNA binding, transcriptional regulation, chromatin modification and signal pathway regulation.;

NCIt note : Transcriptional regulator Kaiso binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated kaiso binding site (KBS) consensus sequence 5'-CTGCNA-3.;

NCI Metathesaurus CUI : CL556217;

Details

Origin ID

C155731;

UMLS CUI

C4723825;

Automatic exact mappings (from CISMeF team)
- Zinc finger- and btb domain-containing protein 33 [OMIM gene]
OMIM relation
- Zinc finger- and btb domain-containing protein 33 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
- ZBTB33 Gene [NCIt concept]
gene_product_expressed_in_tissue
- Vascular Endothelium [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- BTB/POZ Domain [NCIt concept]
- C2H2 Zinc Finger [NCIt concept]
- Nuclear Localization Signal [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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