Rezafungin Acetate

Preferred Label : Rezafungin Acetate;

NCIt definition : The acetate form of rezafungin, a next-generation, semi-synthetic, cyclic lipopeptide and echinocandin derivative, with potential antifungal activity. Upon administration, rezafungin inhibits the fungal specific enzyme 1,3-beta-D-glucan synthase, which is essential for fungal cell wall synthesis, and results in decreased synthesis of beta(1,3)-D-glucan. This weakens the fungal cell wall thereby causing osmotic lysis, fungal cell wall rupture and fungal cell death.;

UNII : W1U1TMN677;

InChIKey : MXMWJAPNUIKPGF-MLAUIKIVSA-N;

CAS number : 1631754-41-0;

NCI Metathesaurus CUI : CL553410;

Details

Origin ID

C152206;

UMLS CUI

C4726688;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- rezafungin acetate [ATC Code]
Validated automatic mappings to BTNT
- rezafungin acetate [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Rezafungin [NCIt concept]
is_salt_form_of
- Rezafungin [NCIt concept]

Keyword's position in hierarchy(ies) :

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