Rezafungin - CISMeF

Preferred Label : Rezafungin;

NCIt definition : A next-generation, semi-synthetic, cyclic lipopeptide and echinocandin derivative, with potential antifungal activity. Upon administration, rezafungin inhibits the fungal specific enzyme 1,3-beta-D-glucan synthase, which is essential for fungal cell wall synthesis, and results in decreased synthesis of beta(1,3)-D-glucan. This weakens the fungal cell wall thereby causing osmotic lysis, fungal cell wall rupture and fungal cell death.;

UNII : G013B5478J;

InChIKey : LNFCWEXGZIEGJW-AMIBTTDLSA-O;

CAS number : 1396640-59-7;

NCI Metathesaurus CUI : CL553409;

Details

Origin ID

C152205;

UMLS CUI

C4726687;

Currated CISMeF NLP mapping
- Rezafungin [MeSH concept]
- Rezafungin [MeSH Supplementary Concept]
- Rezafungin [SMS substance]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Rezafungin [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Rezafungin Acetate [NCIt concept]
is_free_acid_or_base_form_of
- Rezafungin Acetate [NCIt concept]

Keyword's position in hierarchy(ies) :

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