IKBKE wt Allele

Preferred Label : IKBKE wt Allele;

NCIt synonyms : KIAA0151; IKKE; IKKI; IKK-E; IKK-I; Inhibitor of Nuclear Factor Kappa B Kinase Subunit Epsilon wt Allele; Inhibitor of Kappa Light Polypeptide Gene Enhancer in B Cells, Kinase of, Epsilon Gene; Inhibitor of Kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase Epsilon Gene;

NCIt definition : Human IKBKE wild-type allele is located in the vicinity of 1q32.1 and is approximately 27 kb in length. This allele, which encodes inhibitor of nuclear factor kappa-B kinase subunit epsilon, is involved in the modulation of both interferon expression and the nuclear factor kappa-B signaling pathway. Amplification and overexpression of the gene is associated with breast carcinoma.;

NCI Metathesaurus CUI : CL545857;

GenBank Accession Number : AB016590;

Details

Origin ID

C147988;

UMLS CUI

C4553634;

Automatic exact mappings (from CISMeF team)
- Inhibitor of nuclear factor kappa-b kinase, subunit epsilon [OMIM gene]
OMIM relation
- Inhibitor of nuclear factor kappa-b kinase, subunit epsilon [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 1q32.1 [NCIt concept]
gene_is_element_in_pathway
- Cytosolic DNA-Sensing Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Immune Response Process [NCIt concept]
- Interferon Signaling Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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