Interleukin-23 Receptor Complex

Preferred Label : Interleukin-23 Receptor Complex;

NCIt synonyms : IL23R/IL12RB1 Complex; IL23R; Interleukin-23 Receptor; IL-23 Receptor; IL-23R; Interleukin 23 Receptor;

NCIt definition : A heterodimeric complex composed of interleukin-12 receptor subunit beta-1 and interleukin-23 receptor. This receptor complex binds to interleukin-23, which activates the JAK-STAT signaling pathway and modulates the activation of T-lymphocytes, natural killer cells and some myeloid lineage cells.;

Details

Origin ID

C147560;

UMLS CUI

C4553324;

Automatic exact mappings (from CISMeF team)
- Interleukin 23 receptor [OMIM gene]
- interleukin 23 receptor [ORDO Gene]
- interleukin 23 receptor [HGNC gene]
- interleukin-23 receptor activity [GO term]
- interleukin-23 receptor complex [GO term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_product_has_biochemical_function
- Cytokine Receptor [NCIt concept]
gene_product_plays_role_in_biological_process
- Antimicrobial Effect [NCIt concept]
- Cytokine Signaling [NCIt concept]
- NK Cell Activation [NCIt concept]
- T-Cell Activation [NCIt concept]
has_gene_product_element
- Interleukin-12 Receptor Subunit Beta-1 [NCIt concept]
- Interleukin-23 Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

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