Tabelecleucel - CISMeF

Preferred Label : Tabelecleucel;

NCIt synonyms : EBV-CTLs; CTLs ATA129; Allogeneic EBV-specific CTLs ATA129; Allogeneic EBV-specific Cytotoxic T-lymphocytes;

NCIt definition : Allogeneic cytotoxic T-lymphocytes (CTLs) selective for the tumor-associated antigens (TAAs) expressed by the Epstein-Barr virus (EBV), with potential immunostimulating and antineoplastic activities. Upon administration, and after hematopoietic cell transplants (HCT) or solid organ transplants (SOT), or during certain other immunocompromised states, tabelecleucel targets and binds to EBV-associated antigens expressed on EBV-infected cells. This results in lysis of EBV-infected cells and prevents growth of EBV-associated cancer cells. EBV is associated with a variety of cancers and post-transplant lymphoproliferative disorders (EBV PTLD).;

UNII : G3NJ7M8N4H;

Drug name : Teb-cel; Tab-cel; Ebvallo;

Molecule name : ATA-129; ATA 129;

NCI Metathesaurus CUI : CL541621;

Codes from synonyms : 114494;

Details

Origin ID

C143140;

UMLS CUI

C4684961;

False automatic mappings
- tetrasomy [MeSH Descriptor]
Semantic type(s)
- Cell [UMLS semantic type]
UMLS correspondences (same concept)
- tabelecleucel [ATC Code]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Epstein-Barr Virus [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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