NECTIN2 wt Allele

Preferred Label : NECTIN2 wt Allele;

NCIt synonyms : PVRR2; CD112; PVRL2; Poliovirus Receptor-Related 2 Gene; Nectin Cell Adhesion Molecule 2 wt Allele; Nectin 2 Gene; PRR2; Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) Gene; HVEB; Poliovirus Receptor-Like 2 Gene;

NCIt definition : Human NECTIN2 wild-type allele is located in the vicinity of 19q13.32 and is approximately 43 kb in length. This allele, which encodes nectin-2 protein, is involved in viral entry, adherens junction organization and the modulation of receptor-mediated signaling in T-cells. Variation in the gene in subjects with multiple sclerosis may be associated with the severity of the disorder.;

NCI Metathesaurus CUI : CL540245;

GenBank Accession Number : X80038;

Details

Origin ID

C142201;

UMLS CUI

C4553234;

Automatic exact mappings (from CISMeF team)
- Nectin cell adhesion molecule 2 [OMIM gene]
- Nectins [MeSH Descriptor]
OMIM relation
- Nectin cell adhesion molecule 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 19q13.32 [NCIt concept]
gene_is_element_in_pathway
- Adherens Junction Assembly Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Adhesion Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Virus-Cell Membrane Interaction [NCIt concept]

Keyword's position in hierarchy(ies) :

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