Proglucagon - CISMeF

Preferred Label : Proglucagon;

NCIt synonyms : Preproglucagon; Pro-Glucagon;

NCIt definition : Proglucagon (180 aa, 21 kDa) is encoded by the human GCG gene. This protein is involved in appetite, digestion, and glucose metabolism and homeostasis.;

NCIt note : Preproglucagon is a precursor for glicentin, glicentin-related polypeptide (GRPP), oxyntomodulin (OXY, OXM), glucagon, glucagon-like peptide 1 (GLP-1), glucagon-like peptide 1(7-37) (GLP-1(7-37)), glucagon-like peptide 1(7-36) (GLP-1(7-36)), and glucagon-like peptide 2 (GLP-2). (UniProt);

Details

Origin ID

C136747;

UMLS CUI

C4520795;

Automatic exact mappings (from CISMeF team)
- preproglucagon [MeSH concept]
Currated CISMeF NLP mapping
- Proglucagon (substance) [SNOMED CT concept]
- proglucagon [MeSH concept]
- proglucagon [MeSH Descriptor]
- proglucagon [Artificial nutrition thesaurus concept]
- proglucagon, nos [SNOMED Notion]
OMIM relation
- Glucagon [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- GCG Gene [NCIt concept]
- Peptide Hormone Gene [NCIt concept]
gene_product_is_element_in_pathway
- FOXA1 Transcription Factor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Intercellular Communication Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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