MeSH definition : The common precursor polypeptide of pancreatic GLUCAGON and intestinal GLUCAGON-LIKE
PEPTIDES. Proglucagon is the 158-amino acid segment of preproglucagon without the
N-terminal signal sequence. Proglucagon is expressed in the PANCREAS; INTESTINES;
and the CENTRAL NERVOUS SYSTEM. Posttranslational processing of proglucagon is tissue-specific
yielding numerous bioactive peptides.;
The common precursor polypeptide of pancreatic GLUCAGON and intestinal GLUCAGON-LIKE
PEPTIDES. Proglucagon is the 158-amino acid segment of preproglucagon without the
N-terminal signal sequence. Proglucagon is expressed in the PANCREAS; INTESTINES;
and the CENTRAL NERVOUS SYSTEM. Posttranslational processing of proglucagon is tissue-specific
yielding numerous bioactive peptides.