LIMK2 wt Allele

Preferred Label : LIMK2 wt Allele;

NCIt synonyms : LIM Domain Kinase 2 wt Allele;

NCIt definition : Human LIMK2 wild-type allele is located in the vicinity of 22q12.2 and is approximately 68 kb in length. This allele, which encodes LIM domain kinase 2 protein, plays a role in serine/threonine phosphorylation.;

NCIt note : Mutations in the LIMK2 gene may be associated with colorectal cancer. (Nature Communications. 2016; 7: doi:10.1038/ncomms11883.);

NCI Metathesaurus CUI : CL521194;

GenBank Accession Number : D45906;

Details

Origin ID

C132131;

UMLS CUI

C4330525;

OMIM relation
- Lim domain kinase 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 22q12.2 [NCIt concept]
gene_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Axon Guidance Pathway [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
gene_plays_role_in_process
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients