NR1H3 wt Allele

Preferred Label : NR1H3 wt Allele;

NCIt synonyms : Nuclear Receptor Subfamily 1, Group H, Member 3 Gene; RLD-1; LXR-a; LXRA; LX Receptor, Alpha Gene; Nuclear Receptor Subfamily 1 Group H Member 3 wt Allele; Liver X Receptor, Alpha Gene;

NCIt definition : Human NR1H3 wild-type allele is located in the vicinity of 11p11.2 and is approximately 21 kb in length. This allele, which encodes oxysterols receptor LXR-alpha protein, plays a role in both cholesterol homeostasis and the expression of retinoid-responsive genes.;

NCI Metathesaurus CUI : CL520090;

GenBank Accession Number : U22662;

Details

Origin ID

C132114;

UMLS CUI

C4321257;

Automatic exact mappings (from CISMeF team)
- Liver X Receptors [MeSH Descriptor]
- Nuclear receptor subfamily 1, group H, member 3 [ORDO Gene]
- Nuclear receptor subfamily 1, group h, member 3 [OMIM gene]
OMIM relation
- Nuclear receptor subfamily 1, group h, member 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 11p11.2 [NCIt concept]
gene_is_element_in_pathway
- Insulin Resistance Pathway [NCIt concept]
- Lipid Metabolism and Toxicity Pathway [NCIt concept]
- PPAR Pathway [NCIt concept]
- PPAR-alpha Gene Regulation Pathway [NCIt concept]
- RXR and RAR Heterodimerization with Other Nuclear Receptor Signaling Pathway [NCIt concept]
- Regulation of Cholesterol Metabolism Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- Cholesterol Homeostasis [NCIt concept]
- DNA Binding [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Maturation [NCIt concept]
- Pattern Formation [NCIt concept]
- Receptor Signaling [NCIt concept]
- Steroid Metabolic Process [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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