Aldehyde Dehydrogenase 1 Family

Preferred Label : Aldehyde Dehydrogenase 1 Family;

NCIt synonyms : Aldehyde Dehydrogenase Family; Aldehyde Dehydrogenase Class 1; Aldehyde Dehydrogenase 1; ALDH1 Family; ALDH1;

NCIt definition : A polymorphic family of intracellular enzymes that catalyze the oxidation of aldehydes and yield carboxylic acids. High aldehyde dehydrogenase 1 activity may indicate the presence of stem cells or cancer stem cells (CSC) in a sample.;

NCIt note : The ALDH1 family includes proteins encoded by the human ALDH1A1, ALDH1A2, ALDH1A3, ALDH1B1, ALDH1L1, and ALDH1L2 genes.;

Details

Origin ID

C129434;

UMLS CUI

C5235271;

Automatic exact mappings (from CISMeF team)
- Aldehyde Dehydrogenase 1 Family [MeSH concept]
Currated CISMeF NLP mapping
- Aldehyde Dehydrogenase 1 Family [MeSH Descriptor]
See also inter- (CISMeF)
- Aldehyde dehydrogenase 1 family, member a1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Aldehyde Dehydrogenase 1 Family [MeSH Descriptor]
Validated automatic mappings to BTNT
- Aldehyde Dehydrogenase 1 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_biochemical_function
- Oxidoreductase [NCIt concept]
gene_product_plays_role_in_biological_process
- Detoxification [NCIt concept]
- Oxidation/Reduction [NCIt concept]
is_chemical_classification_of_gene_product
- Aldehyde Dehydrogenase X, Mitochondrial [NCIt concept]
- Retinal Dehydrogenase 1 [NCIt concept]
- Retinal Dehydrogenase 2 [NCIt concept]
is_target
- ALDH1/3 Inhibitor ABD-3001 [NCIt concept]

Keyword's position in hierarchy(ies) :

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