Preferred Label : Topoisomerase I/II Inhibitor NEV-801;
NCIt synonyms : TopI/II NEV-801;
NCIt definition : A multi-targeted agent with potential antineoplastic activity. Upon administration,
NEV-801 appears to selectively inhibit topoisomerase (Topo) I and II, and activates
hypoxia-inducible factor 1 (HIF-1) transcription and the expression of vascular endothelial
growth factor (VEGF) mRNA. NEV-801 is also able to overcome multidrug resistance (MDR)
1-mediated resistance.;
Molecule name : NEV-801;
NCI Metathesaurus CUI : CL507943;
Origin ID : C128557;
UMLS CUI : C4287726;
Semantic type(s)
- concept_is_in_subset
- has_target
