Protein GREB1 - CISMeF

Preferred Label : Protein GREB1;

NCIt synonyms : Gene Regulated In Breast Cancer 1 Protein;

NCIt definition : Protein GREB1 (1949 aa, 216 kDa) is encoded by the human GREB1 gene. This protein may be involved in estrogen-stimulated cell proliferation.;

NCIt note : There are at least four isoforms of protein GREB1 produced by alternative splicing. The canonical isoform is GREB1a. GREB1b and GREB1c share 449 and 386 N-terminal amino acids with GREB1a, respectively and have shorter, divergent C-terminal regions. The fourth isoform is an N-terminally truncated form that is comprised of the 947 C-terminal amino acids found in GREB1a. (UniProt and OMIM);

Details

Origin ID

C128184;

UMLS CUI

C4287913;

Automatic exact mappings (from CISMeF team)
- Greb1 protein [OMIM gene]
OMIM relation
- Greb1 protein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- GREB1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Exosome [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- MTA3 Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cancer Cell Growth Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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