Preferred Label : Alanylglutamine;
NCIt synonyms : L-alanyl/L-glutamine; L-alanyl-L-glutamine; Alanyl-glutamine; Ala-Gln; AG; N(2)-L-Alanyl-L-glutamine;
NCIt related terms : ALANYL GLUTAMINE;
NCIt definition : A nutritional supplement containing a stable, water-soluble dipeptide comprised of
the amino acids L-glutamine and L-alanine, with potential protective and absorption
enhancing activities. Upon oral or enteral administration, alanylglutamine works locally
in the gastrointestinal (GI) tract to both protect the integrity of the intestinal
mucosa and maintain intestinal barrier functions. This reduces bacterial translocation,
the risk of infection, infection-induced inflammatory damage and infection-associated
symptoms, such as diarrhea, dehydration, malabsorption and electrolyte imbalances.
Alanylglutamine also increases absorption of other chemicals, enhances epithelial
repair, and inhibits apoptosis due to cellular damage, and stimulates cellular proliferation.
Altogether, this improves absorption of nutrients, decreases weight loss, reduces
diarrhea, decreases the risk of GI-associated infections and improves recovery. Upon
absorption, alanylglutamine may also help inhibit muscle protein catabolism.;
UNII : U5JDO2770Z;
InChIKey : HJCMDXDYPOUFDY-WHFBIAKZSA-N;
CAS number : 39537-23-0;
Drug name : Sustamine;
Origin ID : C127908;
UMLS CUI : C0051080;
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
False automatic mappings
- aging [CISMeF Querying Strategy]
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
concept_is_in_subset