" /> Aging - CISMeF





Preferred Label : Aging;

Type : Phenotype, molecular basis known;

Description : Progressive damage to mitochondrial DNA (mtDNA) during life is thought to contribute to aging processes. This notion is supported by the observation of an aging-related accumulation in human mtDNA of oxidative and alkylation derivatives of nucleotides, of small deletions and insertions, and of large deletions, although their low frequency raises questions about their functional significance (Michikawa et al., 1999).;

Prefixed ID : #502000;

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15/05/2024


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