Pegol-sihematide Injection

Preferred Label : Pegol-sihematide Injection;

NCIt definition : A synthetic peptide derived from erythropoietin (EPO) linked to polyethylene glycol (PEG), with erythropoietic stimulating activity. Upon administration, pegol sihematide binds to and activates EPO receptors on the surface of erythroid progenitor cells in the bone marrow resulting in their differentiation and proliferation. This increases the production of red blood cells and prevents anemia. Pegylation increases this agent's blood circulation time.;

Molecule name : EPO-018B; EPO 018B;

Details

Origin ID

C125064;

UMLS CUI

C4086733;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_gene_product
- Erythropoietin Receptor [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Receptor Activation Process [NCIt concept]
chemical_or_drug_has_physiologic_effect
- B-Cell Activation [NCIt concept]
- Hematopoiesis Induction [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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