MDH2 wt Allele

Preferred Label : MDH2 wt Allele;

NCIt synonyms : Malate Dehydrogenase 2, NAD (Mitochondrial) Gene; M-MDH; MDH; MGC:3559; Malate Dehydrogenase 2 wt Allele; MOR1;

NCIt definition : Human MDH2 wild-type allele is located within 7cen-q22 and is approximately 19 kb in length. This allele, which encodes malate dehydrogenase, mitochondrial protein, is involved in the metabolism of malate and the synthesis of oxaloacetate.;

NCIt note : Ensembl and HGNC report that this gene is located in the vicinity of 7q11.23.;

GenBank Accession Number : NM_005918;

Details

Origin ID

C124984;

UMLS CUI

C4085195;

Automatic exact mappings (from CISMeF team)
- (S)-mandelate dehydrogenase activity [GO term]
- L-malate dehydrogenase activity [GO term]
- Opioid receptor, mu-1 [OMIM gene]
- alcohol dehydrogenase (acceptor) activity [GO term]
- hodgkin disease [MeSH Descriptor]
OMIM relation
- Malate dehydrogenase, mitochondrial [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- Citrate Cycle (TCA Cycle) Pathway [NCIt concept]
- Cysteine and Methionine Metabolism Pathway [NCIt concept]
- Glyoxylate and Dicarboxylate Metabolism Pathway [NCIt concept]
- Pyruvate Metabolism Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Respiration [NCIt concept]
- Gluconeogenic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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