" /> Exisulind - CISMeF





Preferred Label : Exisulind;

NCIt synonyms : Sulindac Sulfone; (Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic Acid; 1H-Indene-3-acetic Acid, 5-Fluoro-2-methyl-1-((4-(methylsulfonyl)phenyl)methylene), (Z);

NCIt definition : An inactive metabolite of the nonsteroidal, anti-inflammatory agent sulindac. After oral administration, sulindac undergoes extensive biotransformation including irreversible oxidation to sulindac sulfone. Approximately, one half of an administered dose of sulindac is eliminated through the urine, mostly as the conjugated sulfone metabolite. (NCI04);

Alternative definition : NCI-GLOSS: A drug being studied in the treatment and prevention of cancer. It has been shown to cause apoptosis (cell death) in cells that are malignant (cancer) and in cells that may become cancer. It acts through a group of cellular enzymes called cGMP phosphodiesterases.;

UNII : K619IIG2R9;

InChIKey : MVGSNCBCUWPVDA-MFOYZWKCSA-N;

CAS number : 59973-80-7;

Drug name : Aptosyn;

Molecule name : FGN-1;

Chemical formula : C20H17FO4S;

NSC code : 719619;

ChEBI ID : CHEBI:64212;

Codes from synonyms : NSC0719619; 08937; CDR0000046015;

Détails


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28/07/2025


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