sulindac sulfone

Preferred Label : sulindac sulfone;

MeSH note : inhibits K-ras-dependent cyclooxygenase-2; sulfated analog of indomethacin;; CP248 is an antineoplastic agent that fosters microtubule depolymerization; structure in first source;

CISMeF synonym : (5-fluoro-2-methyl-1-(3,4,5-trimethoxybenzylidene)-3-(N-benzyl)-indene)-acetamide; CP248; FGN-1; aptosyn;

MeSH synonym : exisulind;

MeSH hyponym : 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfonyl)phenyl)methylene)-, (Z)-; OSIP486823; OSIP-486823; CP 248; OSIP 486823;

MeSH Related Number : sulindac sulfone, (Z)-isomer; 59864-04-9 (sulindac sulfone); 59973-80-7 ((Z)-isomer);

Registry Number MeSH : 59864-04-9;

Related CAS MeSH : 59973-80-7 (sulindac sulfone, (Z)-isomer);

related registry number list (CISMeF) : 59973-80-7 ((Z)-isomer);

Is substance : O;

UNII : K619IIG2R9;

InChIKey : MVGSNCBCUWPVDA-MFOYZWKCSA-N;

Details

Origin ID

C025463;

UMLS CUI

C0075616;

Currated CISMeF NLP mapping
- Exisulind [NCIt concept]
MeSH term(s) associated for indexing
- sulindac [MeSH Descriptor]
Pharmacological action(s)
- anticarcinogenic agents [MeSH Descriptor]
- cyclooxygenase inhibitors [MeSH Descriptor]
Record concept(s)
- (5-fluoro-2-methyl-1-(3,4,5-trimethoxybenzylidene)-3-(N-benzyl)-indene)-acetamide [MeSH concept]
- CP248 [MeSH concept]
- FGN-1 [MeSH concept]
- aptosyn [MeSH concept]
- sulindac sulfone [MeSH concept]
- sulindac sulfone, (Z)-isomer [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Exisulind [NCIt concept]

Keyword's position in hierarchy(ies) :

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