Preferred Label : Curcumin-based Gel;
NCIt synonyms : Curcumin Gel; Topical Curcumin;
NCIt definition : A proprietary topical gel formulation containing an extract of curcumin, the polyphenol
derived from the plant Curcuma longa, with potential anti-inflammatory, antioxidant,
and wound healing activities. Upon topical administration to the affected areas, curcumin
inhibits a variety of pro-inflammatory enzymes and reduces the production of certain
pro-inflammatory mediators. Curcumin also blocks the formation of reactive oxygen
species (ROS), neutralizes free radicals and prevents oxidative stress and DNA damage.
In addition, curcumin inhibits phosphorylase kinase (PhK) in the skin, which prevents
multiple PhK-mediated signal transduction pathways that are induced upon skin injury.
This further prevents inflammation, promotes healing and reduces scar tissue formation.
The proprietary curcumin-based gel also provides moisture to the skin and contains
tetrahydropiperine (THP), which is derived from black pepper fruit and increases skin
uptake of curcumin.;
Drug name : Psoria-Gold;
Origin ID : C122708;
UMLS CUI : C4055175;
Semantic type(s)
- concept_is_in_subset
- has_target
