" /> Elacestrant - CISMeF





Preferred Label : Elacestrant;

NCIt synonyms : SERD/SERM RAD1901; (6R)-6-(2-(Ethyl((4-(2- (ethylamino)ethyl)phenyl)methyl)amino)-4-methoxyphenyl)- 5,6,7,8-tetrahydronaphthalen-2-ol;

NCIt definition : An orally available, selective estrogen receptor degrader (SERD), with antineoplastic activity. Upon oral administration, elacestrant acts as a SERD, which binds to the estrogen receptor (ER) and induces a conformational change that results in the proteosomal degradation of the receptor. This prevents ER-mediated signaling and inhibits proliferation of ER-expressing cancer cells.;

UNII : FM6A2627A8;

InChIKey : SIFNOOUKXBRGGB-AREMUKBSSA-N;

CAS number : 722533-56-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 722533-56-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : ER-306323; RAD1901;

Codes from synonyms : 18359;

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15/05/2024


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