Elacestrant Hydrochloride

Preferred Label : Elacestrant Hydrochloride;

NCIt synonyms : RAD1901 Dihydrochloride; RAD-1901 Dihydrochloride;

NCIt definition : The hydrochloride salt form of elacestrant, an orally available, selective estrogen receptor degrader (SERD), with antineoplastic activity. Upon oral administration, elacestrant acts as a SERD, which binds to the estrogen receptor (ER) and induces a conformational change that results in the proteosomal degradation of the receptor. This prevents ER-mediated signaling and inhibits proliferation of ER-expressing cancer cells.;

UNII : 8NZT0PR8AL;

InChIKey : XGFHYCAZOCBCRQ-FBHGDYMESA-N;

CAS number : 1349723-93-8;

Drug name : Orserdu;

NCI Metathesaurus CUI : CL1406073;

Details

Origin ID

C171898;

UMLS CUI

C4704989;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_free_acid_or_base_form
- Elacestrant [NCIt concept]
is_component_of_chemotherapy_regimen
- Elacestrant Regimen [NCIt concept]
is_salt_form_of
- Elacestrant [NCIt concept]

Keyword's position in hierarchy(ies) :

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