NCIt definition : The hydrochloride salt form of elacestrant, an orally available, selective estrogen
receptor degrader (SERD), with antineoplastic activity. Upon oral administration,
elacestrant acts as a SERD, which binds to the estrogen receptor (ER) and induces
a conformational change that results in the proteosomal degradation of the receptor.
This prevents ER-mediated signaling and inhibits proliferation of ER-expressing cancer
cells.;