N(6)-Carboxymethyllysine

Preferred Label : N(6)-Carboxymethyllysine;

NCIt synonyms : L-Lysine, N6-(Carboxymethyl)-; N(Epsilon)-(Carboxymethyl)Lysine; N(Epsilon)-Carboxymethyl-L-Lysine; CML; NECML;

NCIt definition : A lysine derivative found in proteins where the epsilon nitrogen of the amino acid residue is modified by a carboxymethyl group. This advanced glycation end product (AGE) is elevated in certain diseases and is associated with aging.;

UNII : 70YDX3Z2O7;

CAS number : 5746-04-3;

ChEBI ID : CHEBI:53014;

Details

Origin ID

C120013;

UMLS CUI

C0083528;

Automatic exact mappings (from CISMeF team)
- BCR activator of RhoGEF and GTPase [ORDO Gene]
- CML [MedDRA LLT]
- Chronic myeloid leukaemia, not elsewhere classified [ICD-11 Subcategory]
- Leukemia, chronic myeloid [OMIM Phenotype]
- N(6)-carboxymethyllysine [MeSH concept]
- N(6)-carboxymethyllysine [MeSH Supplementary Concept]
- chronic leukemia [DO Concept]
- chronic myeloid leukemia [DO Concept]
- chronic myeloid leukemia [MedlinePlus Topic]
- immunity, cellular [MeSH Descriptor]
- leukemia, myelogenous, chronic, bcr-abl positive [MeSH Descriptor]
False automatic mappings
- Chronic myeloid leukemia [ORDO Disease]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- N(6)-carboxymethyllysine [MeSH Supplementary Concept]
- N(6)-carboxymethyllysine [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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