Amyloid-Like Protein 1

Preferred Label : Amyloid-Like Protein 1;

NCIt synonyms : APLP; Amyloid Precursor-Like Protein 1; APLP-1; Amyloid Precursor-Like Protein;

NCIt definition : Amyloid-like protein 1 (650 aa, 72 kDa) is encoded by the human APLP1 gene. This protein plays a role in the mediation of postsynaptic signaling.;

NCIt note : Amyloid-like protein 1 is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. (EntrezGene);

Details

Origin ID

C119731;

UMLS CUI

C0662273;

Automatic exact mappings (from CISMeF team)
- Amyloid beta a4 precursor-like protein 1 [OMIM gene]
- amyloid beta precursor like protein 1 [HGNC gene]
OMIM relation
- Amyloid beta a4 precursor-like protein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- APLP1 protein, human [MeSH Supplementary Concept]
- APLP1 protein, human [MeSH concept]
gene_encodes_gene_product
- APLP1 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_expressed_in_tissue
- Cerebral Cortex [NCIt concept]
gene_product_has_associated_anatomy
- Postsynaptic Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Prion Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Nervous System Development [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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