NCIt definition : Pro-neuregulin-3, membrane-bound isoform (720 aa, 78 kDa) is encoded by the human
NRG3 gene. This protein plays a role in signaling.;
NCIt note : The active form of the growth factor, neuregulin-3, is produced when proteolytic cleavage
removes 361 amino acids from the C-terminus of pro-neuregulin-3, membrane-bound isoform.
The precursor is a type I membrane protein and the mature form is a secreted protein.
(UniProt);